{"id":1056,"date":"2026-02-24T16:18:44","date_gmt":"2026-02-24T14:18:44","guid":{"rendered":"https:\/\/krebs-feed.com.ua\/?page_id=1056"},"modified":"2026-07-31T12:38:27","modified_gmt":"2026-07-31T09:38:27","slug":"antygelmintni-preparaty","status":"publish","type":"page","link":"https:\/\/krebs-feed.com.ua\/en\/antygelmintni-preparaty\/","title":{"rendered":"Anthelmintic drugs"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"1056\" class=\"elementor elementor-1056\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c0fc3ba e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no e-con e-parent\" data-id=\"c0fc3ba\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9cbc25a elementor-widget elementor-widget-html\" data-id=\"9cbc25a\" data-element_type=\"widget\" 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data-init-show=\"8\">\n            <div class=\"eael-filterable-gallery-item-wrap eael-cf-\u0410\u0434\u0441\u043e\u0440\u0431\u0435\u043d\u0442-\u0422\u043e\u043a\u0441\u0438\u043d\u0456\u0432\" data-search-categories=\"\u0410\u0434\u0441\u043e\u0440\u0431\u0435\u043d\u0442 \u0422\u043e\u043a\u0441\u0438\u043d\u0456\u0432\">\n\t\t\t\t<div class=\"eael-gallery-grid-item\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/ivermektyn\/\"><div class=\"gallery-item-thumbnail-wrap\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"258\" src=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png\" class=\"attachment-medium size-medium wp-image-3235\" alt=\"\" srcset=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png 300w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-1024x881.png 1024w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-768x661.png 768w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-14x12.png 14w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3.png 1220w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div><\/a><div class=\"gallery-item-caption-wrap caption-style-card\"><div class=\"gallery-item-caption-over\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/ivermektyn\/\"><h2 class=\"fg-item-title\">Ivermectin<\/h2><\/a><div class=\"fg-item-content\"><p><a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/vrh\/\">Cattle<\/a>, <a style=\"color: black!important\" href=\"https:\/\/krebs-feed.com.ua\/en\/ptyczi\/\">Bird<\/a>,<a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/svyni\/\"> Pigs<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"eael-filterable-gallery-item-wrap eael-cf-\u0410\u0434\u0441\u043e\u0440\u0431\u0435\u043d\u0442-\u0422\u043e\u043a\u0441\u0438\u043d\u0456\u0432\" data-search-categories=\"\u0410\u0434\u0441\u043e\u0440\u0431\u0435\u043d\u0442 \u0422\u043e\u043a\u0441\u0438\u043d\u0456\u0432\">\n\t\t\t\t<div class=\"eael-gallery-grid-item\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/levamizol\/\"><div class=\"gallery-item-thumbnail-wrap\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"258\" src=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png\" class=\"attachment-medium size-medium wp-image-3235\" alt=\"\" srcset=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png 300w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-1024x881.png 1024w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-768x661.png 768w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-14x12.png 14w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3.png 1220w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div><\/a><div class=\"gallery-item-caption-wrap caption-style-card\"><div class=\"gallery-item-caption-over\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/levamizol\/\"><h2 class=\"fg-item-title\">Levamisole<\/h2><\/a><div class=\"fg-item-content\"><p><a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/vrh\/\">Cattle<\/a>, <a style=\"color: black!important\" href=\"https:\/\/krebs-feed.com.ua\/en\/ptyczi\/\">Bird<\/a>,<a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/svyni\/\"> Pigs<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"eael-filterable-gallery-item-wrap\">\n\t\t\t\t<div class=\"eael-gallery-grid-item\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/albendazol\/\"><div class=\"gallery-item-thumbnail-wrap\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"258\" src=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png\" class=\"attachment-medium size-medium wp-image-3235\" alt=\"\" srcset=\"https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-300x258.png 300w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-1024x881.png 1024w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-768x661.png 768w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3-14x12.png 14w, https:\/\/krebs-feed.com.ua\/wp-content\/uploads\/2026\/04\/bez\u044bmyann\u044bj-1_montazhnaya-oblast-1-3.png 1220w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div><\/a><div class=\"gallery-item-caption-wrap caption-style-card\"><div class=\"gallery-item-caption-over\"><a href=\"https:\/\/krebs-feed.com.ua\/en\/albendazol\/\"><h2 class=\"fg-item-title\">Albendazole<\/h2><\/a><div class=\"fg-item-content\"><p><a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/vrh\/\">Cattle<\/a>, <a style=\"color: black!important\" href=\"https:\/\/krebs-feed.com.ua\/en\/ptyczi\/\">Bird<\/a>,<a style=\"color: black !important\" href=\"https:\/\/krebs-feed.com.ua\/en\/svyni\/\"> Pigs<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>        <\/div>\n                <\/div>\n        \n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-941c164 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no e-con e-parent\" data-id=\"941c164\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f77118f elementor-widget elementor-widget-n-accordion\" data-id=\"f77118f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2590\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2590\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> <i class=\"vc_tta-icon fa fa-medkit\"><\/i> Anthelmintic drugs differ in origin and mechanism of action: <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-chevron-up\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-chevron-down\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2590\" class=\"elementor-element elementor-element-bf48b14 e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no e-con e-child\" data-id=\"bf48b14\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a2f66a4 elementor-widget elementor-widget-text-editor\" data-id=\"a2f66a4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"1502096453493-0d09a8a8-53bf\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\"><div class=\"vc_tta-panel-body\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\"><div id=\"1502096453493-0d09a8a8-53bf\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\"><div class=\"vc_tta-panel-body\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\"><ol><li><strong>Piperazine<\/strong>\u00a0(piperazine sulfate, piperazine phosphate, diethyl carbomazin). These drugs cause paralysis of the neuromuscular system of helminths, have an anticholinergic effect, thereby disrupting the transmission of impulses. Piperazine salts are widely used against ascarids, filariae, and pulmonary nematodes;<\/li><li><strong>Imidazolethiazoles<\/strong>\u00a0(tetramizole, levamisole, pyrantel). The action of these drugs is based on the depolarization of neuromuscular blocking agents, both in nematodes and their hosts. They are used against many nematodes, especially parasitic in the gastrointestinal tract;<\/li><li><strong>Benzimidazoles<\/strong>\u00a0(thiabendazole, mebendazole, parbendazole, oxibendazole, etc.). Drugs in this group usually act on the intestinal cells of helminths, preventing glucose absorption, thereby causing helminth starvation. They are practically harmless to animals. However, helminths develop resistance to them with repeated use. The drugs can be used in groups. They are widely used against nematodes in sheep and horses, less often against cestodes and trematodes;<\/li><li><strong>Avermectins<\/strong>. Of this group, only ivermectin has widespread use against nematodes. The drug enhances the release and binding of gamma-aminobutyric acid in the nerve synapses of helminths. The drug acts as a neurotransmitter, transmitting signals between neurons. Ivermectin disrupts these signals, leading to paralysis of the nematodes;<\/li><li><strong>Organophosphates<\/strong>. Some organophosphorus compounds (dichlorvos, haloxon, trichlorfon) are active against nematodes. They inhibit cholinesterase, which leads to the accumulation of acetylcholine, paralysis of nematodes and their removal from the intestines. This group of drugs is used mainly for horses. The drugs have an additional insecticidal effect, they are used against the larvae of gastrointestinal gadflies;<\/li><li><strong>Salicylanilides<\/strong>\u00a0(nitrosocanate, closantel, nitroxinil, rafoxanide, oxyclozanide, and others). The drugs prevent the production of ATP by the parasite by disrupting oxidative phosphorylation. They are most often used for fascioliasis, and niclosamide against pulmonary helminths.<\/li><\/ol><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2591\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2591\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> <i class=\"vc_tta-icon fa fa-list-ol\"><\/i> Methods and forms of administration of anthelmintic drugs <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-chevron-up\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-chevron-down\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2591\" class=\"elementor-element elementor-element-ebe4641 e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-column-slider-no wpr-equal-height-no e-con e-child\" data-id=\"ebe4641\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5242502 elementor-widget elementor-widget-text-editor\" data-id=\"5242502\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Anthelmintic drugs are most often administered orally in the form of: tablets, dragees, powders with food, drink, in capsules at the root of the tongue and using a probe. For some helminthiasis, the drug is administered rectally. For muscular, pulmonary, hepatic, renal, abdominal and other helminthiasis, anthelmintic drugs are administered parenterally: subcutaneously, intramuscularly, intratracheally, externally.<\/p><p>Anthelmintic drugs are used individually (especially highly toxic to the body of animals and birds) or by group method. The frequency of use may vary. For intestinal helminthiasis, one or two applications are usually sufficient, for other helminthiasis, longer treatment is required. The dose of the drug can be used once or in small doses, if this increases the effectiveness.<\/p><p>Some helminths develop resistance to anthelmintic drugs. This phenomenon is observed when using drugs containing the benzimidazole group. Therefore, it is recommended to alternate the use of drugs belonging to different chemical groups, taking into account the variability of helminth generations.<\/p><p>Caution should be exercised when using anthelmintic drugs, especially when using highly toxic drugs, as poisoning may occur.<\/p><p>When poisoning animals with organophosphorus drugs, atropine is used intramuscularly at a dose of 0.5 mg\/kg (5 ml of 1% solution per 100 kg) - cattle, horses, pigs.<\/p><p>In severe poisoning with relapses, atropine is administered repeatedly at intervals of 6-12 hours. To increase the effectiveness of treatment, 10% calcium chloride solution should be additionally administered intravenously at a dose of 0.5 ml\/kg 1-2 times a day for 2-3 days, 4% glucose solution at a dose of 1 ml\/kg and other drugs (vitamins, cardiac drugs) depending on the indications).<\/p><p>To avoid poisoning, precautions are of great importance:<\/p><ul><li>Preliminary testing of the drug on a small group of farm animals;<\/li><li>Full feeding;<\/li><li>Compliance with instructions for the use of anthelmintic drugs;<\/li><li>Accurate dosage;<\/li><li>Strict adherence to feeding and watering regimens.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\u0410\u041d\u0422\u0418\u0413\u0415\u041b\u042c\u041c\u0406\u041d\u0422\u041d\u0406 \u041f\u0420\u0415\u041f\u0410\u0420\u0410\u0422\u0418 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